Since age, 1, Bice Osei Kuffour has been very adventurous, daring and untouchable. If you hit him with stick, run for your life because he would respond with a stone [Twi meaning for 'Obour'].

Obour was born at "Braha Bebu Me" (Dekyemenso) in the Ashanti Region on 7 November 1981, to Christiana Addo and Reverend B. O. Kuffour.

At the age of six, Obour played many types of drums, especially the Atumpan, in the Juaso-Ashanti Akyem chief's palace where his father used to preside.

Obour was educated at the State Experimental School (Kumasi), the Soul Clinic School (Accra), Garrisson Junior Secondary School (Burma Camp) and Mfantsipim School (Cape Coast).

After finishing secondary school, Obour solicited help from his London-based cousin, J. Amano, who connected him with his personal Soul Records label.

He subsequently released Atentenben which won three awards for Soul Records at the Ghana Music Awards in 2002, including Video of the year.

This, and other songs by the label, led to Soul Records being awarded with Record Label of the Year. The same video won the Best at Our Music Awards (OMA) in 2002.

He was already a celebrity by the time he entered the University of Ghana in 2002 to study Sociology and Music, as a member of Commonwealth Hall (Vandal City).

His second album, entitled Dondo, was led by the track "Nana Obour", which had earlier featured on Soul Records′ Adakamo compilation album.

Dondo also featured such classic tunes as "Mesoodae" and "Palm Wine". "Nana Obour" won the Best Video at both Ghana Music Awards and Ghana Music Awards UK in 2003.

He now owns a pub in Osu and a music production company.

Obour has been used for some national campaigns because of his positive and educative lyrics. He won five awards at the 2005 Ghana Music Awards.

His albums include Atentenben, Akademua, Dondo and Atumpan. He made a duet album with A. B. Crentsil entitled The Best of the Lifes.

He released a socially conscious album and project, One Ghana Peace Project/Obour for President, ahead of the 2008 general elections.

He went on to embark on a Nationwide Peace Campaign.

Obour was selected among 12 other emerging leaders by The African Leadership Initiative to pursue training with the Aspen Global Leadership Network.

He is also currently the President of the Musicians Union of Ghana, the National TB Ambassador of Ghana, Road Safety Ambassador, Executive icon of Youth Icons Africa and a Climate Change Champion for the British Council.

He serves on several executive and advisory boards, including the executive committee of the International Federation of Musicians, University of Ghana School of Performing Arts advisory board, Ghana Music Rights Organisation.