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Two million people have been affected by the massive earthquake that struck central Chile on Saturday, President Michelle Bachelet has said. In a TV address, she said the forces of nature were testing the nation. So far at least 300 people have been confirmed killed in the earthquake that struck in the early hours of Saturday. The 8.8 quake - one of the biggest ever - triggered a tsunami that has been sweeping across the Pacific, although waves were not as high as predicted. Japan is still on high alert, with scores of thousands of people urged to evacuated areas at risk. Tourists stranded Ms Bachelet said the forces of nature had "once again put to the test our ability to deal with adversity and get back on our feet. And we are examining every way to restore all the basic services in the country. But there's still a lot to do". Ms Bachelet said she had declared a state of catastrophe in six regions. Chile is vulnerable to earthquakes, being situated on the Pacific "Ring of Fire" where the Pacific and South American plates meet. The earthquake struck at 0634 GMT, 115km (70 miles) north-east of the city of Concepcion and 325km south-west of the capital Santiago at a depth of about 35km. It is the biggest to hit Chile in 50 years. Widespread damage to roads and buildings has been reported in many areas, including the capital where a chemical plant caught fire. Electricity, water and phone lines have been cut. At least 85 people died in the region of Maule alone, journalists there reported. Many deaths were also reported in the regions of Santiago, O'Higgins, Biobio, Araucania and Valparaiso. TV pictures showed a major bridge at Concepcion had collapsed into the Biobio river. Rescue teams have been searching the wreckage of toppled buildings for survivors. In Santiago, where at least 13 people were killed, several buildings collapsed - including a car park. A fire at a chemical plant in the outskirts of the capital forced the evacuation of the neighbourhood. More than 200 prisoners escaped from a jail in the town of Chillan. About 60 have been recaptured so far and the 600 inmates in custody have been transferred to a facility in Concepcion. The BBC's Candace Piette, who travelled to Santiago by road from the Argentina border, says the drive from the Andes was difficult, with many damaged roads. In the capital the effects are patchy, she says, with many parts still blacked out and some water services cut. Tourists are stranded in hotels unable to leave because of the international airport's closure and some people have been bedding down in city squares, scared to sleep inside. The US Geological Survey (USGS) has recorded numerous aftershocks, the largest of 6.9 magnitude. The airport terminal in Santiago was damaged and will be closed for at least 72 hours, officials said. Flights are being diverted to Mendoza in Argentina.