Democrat presidential candidate Joe Biden has said the second televised debate should not take place if President Donald Trump is still infected.
"I think if he still has Covid, we shouldn't have a debate," Biden said on Tuesday.
"I think we're gonna have to follow very strict guidelines. Too many people have been infected and it's a very serious problem."
The debate is scheduled for 15 October in Miami, Florida.
Trump tested positive on Thursday 1 October, but it's not clear when he caught the virus or began to feel unwell.
According to US public health guidelines, Trump should remain in isolation for up to 10 days after symptoms first appear.
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