Hearts of Oak will be without striker Mahatma Otoo and defender Ahmed Soulama for Sunday�s Premier League game with All Stars.
Otoo, 19, is suspended for accumulated yellow cards while Soulama is out with a bout of malaria.
The duo�s absence presents a problem for coach C.K Akunnor considering their recent surge.
But the ex-Ghana captain believes it opens an opportunity for the others to step prove a point.
�Yes, I can confirm Mahatma Otoo and Soulama are out of Sunday�s against All Stars,� Akunnor told MTNFootball.com after his final training session on Friday.
�Though will be missed I believe their absence presents an opportunity for the others and hopefully they will make good use of it.�
Hearts currently third in the Ghana Premier League will be looking to reduce the gap between them and leaders Asante Kotoko ahead of next week�s derby.