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Sergio Aguero's second-half strike gave Manchester City a fourth successive Premier League victory over 10-man Manchester United at Etihad Stadium. Aguero was twice denied in the first half by David De Gea, before United defender Chris Smalling was sent off. City then took the lead just after the hour as Aguero fired into the roof of the net from Gael Clichy's pass. Robin van Persie and Angel di Maria were both denied by Joe Hart as City held firm for the win. Manuel Pellegrini's side are third, six points behind leaders Chelsea.