The Argentine attacker has contracted the virus along with three other players ahead of the Coupe de France clash with Vannes.
Lionel Messi has tested positive for Covid-19, Paris Saint-Germain have confirmed.
The Argentine attacker will miss the team's clash with Vannes in the Coupe de France on Monday.
The attacker returned to his homeland over the Christmas break, but has since contracted the virus while three team-mates have also tested positive.
What has been said?
"The four players that tested positive for Covid-19 are Leo Messi, Juan Bernat, Sergio Rico and Nathan Bitumazala. They are currently in isolation and are subject to the appropriate health protocol," a statement from PSG read.
Coach Mauricio Pochettino says he is unsure if Messi will be available for next week's Ligue 1 match against Lyon.
He said at a press conference: "I don't know if he will be there against Lyon. He will come back from Argentina when he is negative."
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